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Liu J, Song X, Kuang F, Zhang Q, Xie Y, Kang R, et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 190.Ma Q., Hao S., Hong W., Tergaonkar V., Sethi G., Tian Y., Duan C

A longer half-life is a pharmacokinetic property, not evidence of a better or safer outcome

In obese mouse models: Animals treated with 5-Amino-1MQ lost significant fat mass compared to controls Effects were most pronounced in visceral adipose tissue the metabolically dangerous fat around organs No cardiovascular toxicity or significant off-target effects were observed at research doses Body weight decreased without appetite changes, suggesting the mechanism was purely metabolic Human data is limited this is still a research compound