Administration of E2 has been shown to enhance mitochondrial function in the liver while simultaneously decreasing the production of reactive oxygen species (ROS) and mitigating insulin resistance in rat models (45)
Rosenbloom AB et al (2020) beta-Catenin signaling dynamics regulate cell fate in differentiating neural stem cells
The initial research shows its potential to boost fat burning
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Pellatt, AJ, Bent, AH, Hornstein, N, Parseghian, C, Huey, RW, Raghav, KS, Morris, VK, Overman, MJ, Morelli, P, Willis, JA, Le, PH, Shen, JY, Kee, BK, Eluri, M, Higbie, V, Alfaro-Munoz, KD, Aziz, KE, Kell, R, Sun, R, Kopetz, S , Dasari, NV