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Limitations: Low absorption rate: A significant portion of the NAD+ is broken down in the digestive system before it can reach the bloodstream

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doi:10.1002/ajmg.c.31546 Adil Ghafoor, Sahaana Sundar, Tennekoon Karunaratne, Satish S.C

Jones TE, Pories WJ, Houmard JA, Tanner CJ, Zheng D, Zou K, Coen PM, Goodpaster BH, Kraus WE, Dohm GL

Based on a comprehensive analysis of the literature, we propose that BACH1 is a typical context-dependent transcription factor, and its function is strongly regulated by the intracellular redox state: ROS levels and heme metabolism significantly influence the expression and activity of BACH1