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This makes cagrilintide useful in experimental work focused on integrated metabolic physiology, particularly when researchers want to understand how appetite signaling, endocrine regulation, and energy metabolism interact across tissues [4][6]

Nrf2 is a crucial oxidative-stress-responsive transcription factor that governs the expression of antioxidants and cytoprotective genes, protecting cells against oxidative stress to maintain cellular ROS homeostasis [50]

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doi: 10.1001/jama.2019.14745 213 WangJWangYLiuY