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A 2018 analysis of GHK's gene-expression signature in the Broad Institute Connectivity Map database, published in Aging (Albany NY) , found overlap with gene sets associated with neuroprotection and BDNF upregulation [6]

doi: 10.1186/s12870-016-0773-9

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Based on our earlier findings on the effects of GlyNAC supplementation in other populations and the current finding that people hospitalized with COVID-19 had glutathione deficiency and increased oxidative stress, we considered whether GlyNAC supplementation could also combat these defects in COVID-19 and potentially be valuable in helping the body fight this serious infection

In this synthesis reaction, cysteine serves as the critical rate-limiting factor (53)