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Among them, oxidative stress refers to the excessive accumulation of reactive oxygen species (ROS) that leads to the imbalance of oxidants and antioxidants, oxidative stress has the ability to lead to mitochondrial dysfunction and lysosome dysfunction, and ultimately induces neurodegenerative disease (Caspersen et al., 2005

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GonadotropinReleasing Hormone (GnRH) GnRH was first isolated in the early 1970s from the porcine hypothalamus (220)