When oxidative stress is high and glutathione is low, mitochondrial efficiency drops, leading to fatigue and brain fog
A team of Northwestern investigators led by Peter Penzes, PhD, the Ruth and Evelyn Dunbar Professor of Psychiatry and Behavioral Sciences and director of the Center for Autism and Neurodevelopment, has developed a new therapy that could treat Phelan-McDermid syndrome, a subtype of autism spectrum disorder (ASD), according to findings published in Molecular Psychiatry
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Initially identified for its ability to induce phase II detoxification enzymes and inhibit carcinogenesis, sulforaphane exerted its neuroprotective effects by triggering NRF2-dependent adaptive stress responsesa classic example of hormesis (Butterfield et al., 2023
Cardiovascular and neurovascular injury: Protection in heart ischemia models, eye injuries, and various CNS insults through combined vascular, antiinflammatory, and antioxidative mechanisms