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By inhibiting NNMT, 5-Amino-1MQ: Reduces 1-methylnicotinamide production Preserves intracellular nicotinamide levels Increases NAD+ availability Shifts cellular metabolism toward oxidative pathways Enhances mitochondrial function and energy expenditure Decreases fat storage and adipocyte differentiation These effects support improved metabolic efficiency, reduced adipose tissue accumulation, and preservation of lean mass