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10.1016/j.coi.2025.102658 38 FengX.QiaoJ.XuW

Recent studies have revealed the elevation of SIRT1 in a rat model of status epilepticus, a common neurological emergency which is defined as a prolonged seizure with at least five minutes or multiple seizures with incomplete recovery of consciousness [117] and its neuroprotection is conducted via deacetylation of proliferator-activated receptors and coactivator 1 (PGC-1), an important regulator for mitochondrial biogenesis [118, 119]

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Glutathione is often called the master antioxidant because of its essential role in protecting cells from oxidative stress and supporting overall wellness