Precision medicine approaches should enroll participants based on biological signatures rather than broad diagnostic categories, including glutathione status, lactate to pyruvate ratios, N acetyl aspartate, NRF2 related profiles, electron transport chain complex activity, and the presence of folate receptor alpha autoantibodies in cerebral folate deficiency
FTH1, Ferritin heavy chain 1
Glutathione is a tripeptide made up of three amino acids: cysteine, glycine, and glutamic acid
For those who are pregnant or breastfeeding, scientific data on supplemental glutathione is limited, so it is always best to have a conversation with your healthcare provider first
It has been shown that CTX-induced ovarian toxicity is closely related to ferroptosis in granulosa cells [54]