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144 Other promising PPAR agonists were evaluated in randomized controlled phase 2/3 trials of NASH patients including the dual PPAR/ agonist Saroglitazar (NCT03061721) 145 and a pan-PPAR agonist Lanifibranor (NCT03008070)

Cellular senescence is characterized by a stable arrest in the cell cycle and encompasses a range of cellular changes that culminate in the development of a complex, pro-inflammatory secretory profile known as the senescence-associated secretory phenotype (SASP), which plays a critical role in fibrosis and tumors by affecting numerous processes, including invasion and therapy resistance 10

Patient satisfaction after switching from conventional to new atypical antipsychotics in schizophrenia

Repa, J