Dose-finding studies for CNS effects in humans are needed because extrapolation from rat doses is unreliable
Polymeric prodrugs and nanoassemblies offer controlled drug release and enhanced biocompatibility via polymer carriers
Cracking the pepper mystery Another distinctive wine flavour that has been under the microscope is the cracked black pepper character in Shiraz grown in cool climates
Simple Reconstituting peptides refers to the process of dissolving or rehydrating lyophilized (freeze-dried) peptides to prepare them for use in research
In rat and human tissue, high signals for GHSR1a mRNA are found expressed in several hypothalamic nuclei, the pituitary, and the dentate gyrus of the hippocampus, with additional yet reduced signals in CA2 and CA3 of the hippocampus, the substantia nigra, the ventral tegmental area, and the median raphe nuclei (Guan et al., 1997