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Description

It does not override endocrine signalling

It plays a central role in eliminating free radicals, recycling vitamins C and E, and ensuring proper immune function

The ModA2 phasevarion of nontypeable Haemophilus influenzae regulates resistance to oxidative stress and killing by human neutrophils

Immune cells use ROS to sustain their functions and need adequate levels of antioxidant defenses to avoid harmful effects caused by excessive ROS production, since accurate balance between ROS and intracellular antioxidants is essential for a normal function of the cell (Banjac et al., 2008