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However, these protective mitochondrial adaptations, including mitochondrial dynamics regulation, mitophagy activation, mitochondrial biogenesis augmentation, mitochondrial bioenergetics improvement and mitochondrial anti-oxidative capacity intensification are usually impaired in many cardiovascular diseases [74], which is therefore accompanied by mitochondrial respiratory chain dysfunction, ATP synthesis disorder, oxidative stress and mitochondrial integrity loss [75, 76]

The table above shows the typical toxins introduced into the body with each cigarette smoked

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Laird AR, Fox PM, Eickhoff SB, Turner JA, Ray KL, McKay DR, Glahn DC, Beckmann CF, Smith SM, Fox PT