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3 In addition to disrupting calcium metabolism, lead can mimic and displace magnesium and iron from certain enzymes that construct the building blocks of DNA (nucleotides) and disrupt the activity of zinc in the synthesis of heme (the carrier of oxygen in red blood cells)

Given that both APR-017 and LCS3 are involved in inhibiting the GSH synthesis metabolism pathway, we examined whether the lethal effects of APR-017 and LCS3 on VRK2-deficient cells were due to inhibition of GSH

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Transient facial flushing occurs in some users shortly after injection