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If you experience any severe symptoms outside of minor swelling or bruising at the injection site, including significant pain at the injection site that has not gone away by the next day, call your doctor immediately.

At the cellular level, CKD is remarkable by oxidative stress, abnormal autophagy, and mitochondrial dysfunction accompanied by significant alterations in cell signaling pathways such as HIF, TGF-, and p53 activation [21]

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