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Additionally, it inhibits intestinal Cl - secretion and primarily enhances Na + absorption by blocking TRPV4 channels in transgenic mouse models, including TRPV1- and TRPV4-knockout mice [209]

doi: 10.3390/metabo12121251 85 AimarettiGCorneliGBaldelliRDi SommaCGascoVDuranteCet al

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It reduces hepatic inflammation and oxidative stress by modulating the SIRT1/Nrf2/NF-B axis, thereby restoring liver function

The significant cell damage and loss result in decreased dopamine concentration within the striatum and the dysfunction of the nigrostriatal pathway