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Examples include: Insulin regulates blood sugar in diabetes GLP-1 medications (semaglutide, tirzepatide) used for diabetes and weight management Calcitonin used in bone metabolism disorders These medications underwent years of clinical trials and regulatory review before becoming approved treatments

Some research suggests DSIP helps with reducing sleep latency (the time it takes to fall asleep), enhancing sleep quality promoting slow-wave sleep and supporting the sleep-wake cycle

Its generally well-tolerated with minimal side effects

Dihexa has potential for the study of Alzheimer's disease

While one trial did show VAX-D to be more effective than TENS, concerns about study design, limited generalizability, and safety risks have kept it from being widely accepted as a standard treatment (Aetna Clinical Policy Bulletins, 2025)