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Headache, depression and anxiety: associations in the Eurolight project

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Vascular and angiogenic endpoints include: VEGF expression CD34 markers factor VIII markers vascular density endothelial response eNOS signalling NO pathway markers blood flow related tissue response This pathway helps explain why BPC-157 appears in so many different tissue models

Jain A, Lamark T, Sjottem E, Larsen KB, Awuh JA, Overvatn A, McMahon M, Hayes JD, Johansen T (2010) p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription