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Participating in glutathione binding reactions as a transferase, GST is widely dispersed across the cytoplasm of various cell types, acting as a critical component in the metabolism of numerous intrinsic and extrinsic toxins

In preclinical research, it has been observed to influence local anabolic signaling following mechanical stress

Interestingly, the mice lacking normal microbiota showed low cytotoxicity and deficient free radical production in response to platinum chemotherapy

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