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The compound has been found to operate in the postrema and nucleus of the hindbrain solitary tract in order to both induce satiety and regulate appetite by acting on receptors found in the laterodorsal tegmental nucleus, ventral tegmental area, and the hypothalamus [1]

The "one concentration for the whole protocol" approach Many researchers choose 2.5 mg/mL as their universal concentration because it works reasonably well across the entire titration range

the gelatin shell and enteric coating may degrade at higher temperatures

The metabolomics data and other data supporting this study are available within the Source Data File