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Marihuana is listed in Schedule I of the CSA due to its high potential for abuse, which is attributable in large part to the psychoactive effects of THC, and the absence of a currently accepted medical use of the plant in the United States

Institutional Review Board Statement The study was conducted according to the guidelines of the Declaration of Helsinki, and the procedures involving animals were in accordance with the ethical standards of Nanjing First Hospital (protocol#: DWSY-1901438)