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The insulin resistance paradox This is the primary safety concern, and it deserves detailed explanation

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While freezing did not impact the concentrations of NAD + , NADH, GSH, or GSSG, it triggered the conversion of NADPH to NADP+, with about 508% of NADP + originating from oxidized NADPH (Supplementary Figure 1m-r)

The role of antioxidants Oxidative stress is a process that can be counteracted with antioxidants