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The copper ion is chelated primarily through the imidazole nitrogen of histidine and the alpha-amino nitrogen of glycine, creating a stable, biologically active complex

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Eastwood GL, Beck BD, Castell DO, Brown FC, Fletcher JR

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Effects of hypertension therapy based on eprosartan on systolic arterial blood pressure and cognitive function: primary results of the Observational Study on Cognitive function And Systolic Blood Pressure Reduction open-label study