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Consequently, the direction of LPA-LPAR signaling is primarily determined by the specific G protein subtypes coupled to the involved LPARs, which in turn drive downstream signaling cascades and ultimately regulate various cellular biological behaviors, including proliferation, survival, inflammatory responses, immune responses, migration, and differentiation

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[24] Application of the drug along with the neurotoxin, MPP+, prevented the MPP+-induced death of dopaminergic neurons in both the ventral tegmental area and the substantia nigra

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