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Ive not seen any WOW results for bum filler though, and its VERY product intensive, and with results only lasting around 2 years its expensive for limited gain

The committee's recommendation, while not binding, is heavily weighted in the agency's subsequent decision on permanent listing

In 2026, trials must be designed for external volatility, with greater focus on milestone discipline, funding resilience, and regulatory foresight

What the margin difference looks like in practice: Community sources describe the room-temperature-stored punctured vial as more likely to reach the boundary of preservative efficacy within the 28-day window still technically within the documented period, but with less safety margin