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Our animal models, induced using endothelin-1 (ET-1), reflect clinically relevant cerebral I/R conditions yet may not fully capture the complexity of human pathophysiology, including inter-individual anatomical variation and comorbidities ( in vivo , including their potential off-target effects and clearance pathways

Low concentrations of magnesium and potassium in the body are associated with increased risk of developing ventricular arrhythmias (Sultan 2012)

according to preliminary study, and hydro-distillation process should be carried out repeatedly until no more EO can be extracted

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