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Food and Drug Administrations (FDA) PMTA roundtable on February 10, small manufacturers of electronic nicotine delivery systems (ENDS) questioned the cost, feasibility, and predictability of pharmacokinetic (PK) studies used to assess abuse liability, while FDA officials emphasized that addiction potential remains a necessary component of the agencys determination of whether a product is appropriate for the protection of public health (APPH)

Nicotine Addiction

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But the settlement wasn't changed