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Even if a fragment survives, the intestinal epithelium is a selective barrier: peptides above roughly 500 to 700 daltons struggle to cross via paracellular routes, and transcellular uptake is limited to specific transporter substrates

This is particularly relevant because so many injuries (chronic Achilles tendinopathy, rotator cuff tears) occur in areas with inherently limited blood flow

It can also help prevent cell apoptosis which helps maintain cell viability and contribute to overall mitochondrial function

Interestingly, though, GHK-Cu appears to possess anti-cancer properties

Intramuscular injections are touted as being easier to administer than intravenous, partly because of the easy access of the thigh muscles