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Serum interleukin-17A (IL-17A), RANKL, and OPG levels increase in postmenopausal women with OP, and there are also more peripheral blood CD4+ T cells that produce interleukin-17 (IL-17) (9)

High-dose oral vitamin B12 supplements (1000-2000 micrograms per day) have also been shown to raise levels, because high doses can usually compensate for the bodys poor absorption