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In contrast, e-cigarette vapor contains far fewer harmful substances, such as tar and carbon monoxide, which are major contributors to smoking-related diseases like cancer and heart disease

More specifically, the CO in smoke binds Hb, creating COHb [86] through the following reaction: HbO2 + CO?COHb + O2 where HbO2 is oxyhaemoglobin

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Scents fade over time, requiring frequent reapplication

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