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Factors affecting hydrolysis include: Storage temperature pH Amino acid sequence Buffer composition Time This is why refrigeration dramatically slows degradation

1919 and 2012.2 were cultured in complete NB medium, and 1919 GBM isogenic models, GFP Ctrl, PSPH amp and PSPH V116I were cultured in low glucose complete NB medium

AHA 2014)

Lenvatinib and anti-PD-1 antibody together robustly suppressed tumor growth, induced vascular normalization, and improved anti-PD-1 therapeutic efficacy in HCC (Yang et al., 2023)