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In the nervous system, it is found in the millimolar range in both neuronal and nonneuronal cells, arising endogenously by synthesis from its precursor amino acids or taken up from the blood by means of specific transport mechanisms

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These free radicals, generated as byproducts of normal metabolic processes or introduced through external factors like pollution and UV radiation, can damage cells and contribute to various skin and health issues

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While mild to moderate cases can be managed with non-invasive treatments, severe spinal stenosis often requires surgery