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Strong evidence suggests that metformin, through its protective effects and AMPK-activating properties, can help prevent cancer, cardiovascular disease, obesity and its consequences, and even neurodegenerative disorders

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Although AFLD is usually considered a benign and static lesion, it can develop irreversible liver damage in a short period of time, MASLD is caused by high-fat diet (HFD), high-fructose diet, methionine- and choline-deficient diet (MCD), gene mutations, and heavy-metal poisoning

Second, the peak appetite suppression effect occurs roughly 1-3 days after injection, which aligns well with maintaining dietary discipline during the working days when routine meals are easier to plan