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Evidence Against the Gateway Hypothesis The strongest evidence challenging gateway drug theory as a universal mechanism includes: The National Institute of Justice (2018), after reviewing 23 peer-reviewed studies, concluded no causal link between cannabis use and other illicit drug use can be established, noting that statistical correlation persists across populations but direct pharmacological causation cannot be claimed from observational data alone

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Distributing Information Another primary goal of the AACRs efforts to decrease the prevalence of tobacco use is to inform policymakers, the media, and the public of the links between tobacco and cancer

For updates on all FDA tobacco product activities, visit www.fda.gov/TobaccoProducts