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Protein turnover allows shifts in the quantities of different proteins produced as physiology requires, and removes modified or damaged proteins

In the shuttle, glutamate is converted to glutamine in astrocytes, and then exported to neuronal system A transporters, where it is converted to glutamate intracellularly by phosphate activated glutaminase (21)

These include itsactions on acetylcholine synthesis, membrane stability, nerve growth factor production, and cerebral blood flow

We also uncover a distinct function in iron metabolism, showing PHACTR1 regulates essential cellular iron-storage proteins and identify the PHACTR1 protein within the mitochondria where it directs morphology and bioenergetics through a signaling axis involving AKAP1 and Drp1

GPX Glutathione PeroXidase