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doi: 10.1038/s41574-019-0273-8 5 McDonoughCAChoykeSBartonKEMassSStarlingAPAdgateJLet al

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All SAEs of death, development of signs of critical illness and severe illness requiring hospitalisation, and AEs as described previously will be reported to the Ethics Committees, the Data and Safety Monitoring Board (DSMB) and to the sponsors of the study within 24 hours of awareness of the event, followed by a final report within 10 days

Maintenance dosing after achieving weight loss often allows reduction to 1.8-2.0mg weekly while sustaining results, providing cost savings and better tolerability for long-term use

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