A 2006 Achilles-detachment study by Krivic and colleagues in the same journal applied BPC-157 intraperitoneally once daily at 10 g/kg, 10 ng/kg, or 10 pg/kg for 30 days in rats and reported that tendon-to-bone tissue, which did not heal spontaneously in saline controls, recovered with BPC-157 treatment, with directionally improved load-to-failure, stiffness, Young's modulus, and collagen organization at days 121, including in animals where healing had been impaired by 1 mg/kg 6-methylprednisolone though the abstract does not report numeric effect sizes or p-values
Kodali et al., 2018
CagriSema combined cagrilintide with semaglutide (a single-receptor GLP-1 drug)
Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders
Two animal studies, analysing the effect of TP508 loaded on PPF composite and microsphere scaffolds on segmental bone defects in rabbits, showed enhanced bone formation with a higher torsional stiffness of bone [99, 101]