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Khim., 2010, 56(6), 657-662

[3] Epitalon reduced the number of spontaneous tumors and the number of metastases in mice that did develop spontaneous tumors in an experiment on one-year-old female mice of the C3H/He inbred strain, and is speculated to have oncostatic and anti-metastatic properties

Therefore, spleen deficiency often implies changes in gastrointestinal motility (such as gastric emptying rate), gastrointestinal hormones (such as gastrin), and immune indicators (such as CD4/CD8), while dampness excess often implies changes in blood lipids, cholesterol, and inflammatory factors, such as interleukin-2 (IL-2), interferon-gamma (IFN-), and reactive oxygen species (ROS)

So far, roughly 160 clinical studies with over 10,000 participants have been reported for Pycnogenol

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