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Although region-specific analysis of catalase activity in discrete brain areas offers insights into localized oxidative stress, measurement in whole brain homogenate provides an integrative overview of the general antioxidant status of the brain

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In a mouse model of breast cancer, arginine depletion in the TME by macrophages, differentiated in the presence of transforming growth factor beta (TGF), is associated with the inhibition of CD8 + T cells recruitment, due to the enhanced synthesis of collagen

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558 Furthermore, another Phase II trial (B-Sure) evaluated the durability of bepirovirsens antiviral effect (NCT04954859)