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Most of the GCL holoenzyme can be reversibly dissociated by treatment with dithiothreitol [42], while oxidative stress may enhance holoenzyme formation as it increases GCL activity in the absence of any change in the expression of GCL subunits [45]

For women, zinc plays an essential role in supporting oocyte maturation and maintaining hormonal balance

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Crisol L et al published a study in Fertility Sterility confirmed studies regarding ROS damage to sperm membranes resulting in a negative impact on fertilization