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But systemic estrogen levels also matter, and adipose tissue is a significant source of estrogen production through peripheral aromatase conversion

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Some of these remedies may show temporary improvement in skin tone, but they also come with inherent risks such as allergic reactions, skin irritation and potential damage to the skin barrier

It is one of the main reasons providers prescribe sublingual formulations for patients who could not tolerate injectable tirzepatide due to nausea