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The association of FOXK with DVL can be enhanced by Wnt signalling and is consistent with the improved DVL nuclear translocation capability, which plays a positive role in regulating the Wnt/-catenin signalling pathway

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555 However, an evolutionarily conserved amino acid substitution at the binding site for VHL in HIF-2 results in a 2-3-fold decrease in its binding affinity compared to HIF-1

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Deferoxamine inhibits iron-uptake stimulated osteoclast differentiation by suppressing electron transport chain and MAPKs signaling