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Regarding ROS, Leishmania also controls their production at different levels

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This may not pose a problem until the body becomes overloaded with toxins unfortunately more or less inevitable in todays toxic world

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Animals injected with PKH26-labeled t-butyl hydroperoxide (t-BHP) treated RBCs, to induce oxidative stress, demonstrated an increase in the number of stalled or unmoving RBCs and reduced blood flow velocity in the cerebral vasculature within 14 h and 24-h after RBC injection, as compared to control animals injected with phosphate-buffered saline (PBS) (Zhang et al., 2023)

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