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Research demonstrates TB-500 binds with high affinity to monomeric G-actin, preventing premature polymerization into F-actin filaments and maintaining a pool of unpolymerized actin for rapid cytoskeletal reorganization

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doi: 10.3389/fcimb.2020.00495 119 YooJ

Localized application focuses on injured areas (tendon strain, muscle tear), while systemic use supports overall recovery balance