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(8B, the amount of respiring brain tissue also increases hugely, total rate of energy metabolism in the rat brain cortex must increase about 10 times within these 20 days

Clinically, the treatment strategies during phase I utilize conventional methods: patients should be treated with hypothermia, free radical scavengers (e.g., melatonin, erythropoietin, coenzyme Q10), excitatory amino acid receptor blocking agents, and/or neuroprotective agents

It is currently believed that drugs that may cause arrhythmias (such as flecainide and sotalol) should be used with greater caution, and non-dihydropyridine calcium channel blockers should be avoided in patients with HF (13)

Zhao B, Geisslinger G, Hall I, Day RO, Williams KM (1992) The effect of the enantiomers of ibuprofen and flurbiprofen on the beta-oxidation of palmitate in the rat