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Decreased levels of TNF- and IL-6 indicate that NNMT inhibition not only modulates metabolism but also improves the inflammatory microenvironment, a key component in metabolic disease development and insulin resistance

Acetic acid, acetonitrile, 2-propanol and methanol were purchased from Fisher Scientific (Ottawa, Ontario, Canada)

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Journal of Biological Chemistry, 281 (27), 18774-18786

Then mitochondria burn this fat into useful energy