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Also, BPC 157 was given perorally in drinking water for 4 weeks (12 ml/rat/day, 0.16 g/ml, 0.16 ng/ml) in rats which underwent ibuprofen application for 4 weeks while controls were drinking water only

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In essence, radical reactions circumvent the spin barrier limiting triplet oxygen reactivity, thus driving thermodynamically favorable lipid oxidation, leading to the disruption of membrane integrity and function