For example, L-ascorbic acid, a form of vitamin C found in many skin care products, degrades when it is exposed to heat, a high pH or sunlight, she said which can happen during transit and storage. And then theres the question of sufficient penetration into the skin barrier to allow Vitamin C to do what it needs to do to truly promote your skin health
Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes
Sun S, Wang Y, Wu A, Ding Z, Liu X
Environmental and medication exposure Frequent use of sulphur-containing medicines (e.g., sulfa drugs) or certain supplements (like MSM) can overwhelm detox capacity
These temporary setbacks, while frustrating, resolve with appropriate management