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Prior to commencing the experiments, the cigarette filters were sterilized using UV light for 30 min to eliminate any interfering factors

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We found ferroptotic type I alveolar epithelial cells (CD71 + HOPX + ) and ferroptotic type II alveolar epithelial cells (CD71 + proSP-C + ) are both elevated after ENDS exposure ( Figures 7A, B , Supplementary Figures 1B, C ), suggesting that ENDS induced ferroptosis in epithelial cells, which is partially responsible for alveolar degradation and destruction

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